The thrifty phenotype and fetal overnutrition hypotheses are two developmental hypotheses that originated from the "developmental origins of health and disease" (DOHaD) perspective. The DOHaD posits that exposures experienced prenatally and early in life may influence health outcomes through altering form and function of internal organs…

This study examines interactions of heritable influences, prenatal substance use, and postnatal parental warmth and hostility on the development of conduct problems in middle childhood for boys and girls. Participants are 561 linked families, collected in 2 cohorts, including birth parents, adoptive parents, and adopted children. Heritable…

This study used a prospective adoption design to investigate effects of prenatal and postnatal parent depressive symptom exposure on child hypothalamic-pituitary-adrenal (HPA) activity and associated internalizing symptoms. Birth mother prenatal symptoms and adoptive mother/father postnatal (9-month, 27-month) symptoms were assessed with the Beck…

Poor executive functioning has been implicated in children's concurrent and future behavioral difficulties, making work aimed at understanding processes related to the development of early executive function (EF) critical for models of developmental psychopathology. Deficits in EF have been associated with adverse prenatal experiences, genetic…

As the number of international adoptions has increased over the past 2 decades, so has awareness and understanding of the risks associated with the conditions to which these children have been exposed. Prenatal alcohol and/or drug exposure, infectious diseases, malnutrition, and psychosocial deprivation all contribute to the profound growth and…

This study is based on a statewide longitudinal sample of adopted foster youth and explores the relationship between early pre-adoption risk factors and subsequent elevated levels of psychopathology symptomatology. One central goal of the study was to evaluate the impact of preadoption stressors (prenatal drug/nicotine exposure, early…

Prenatally drug-exposed and not drug-exposed children adopted as infants and older children were compared four years after adoption on a range of outcome indicators. Drug-exposed and not drug-exposed children were alike on most outcome indicators, and parental satisfaction with the adoption was high and equivalent for parents of both groups. (TJQ)

Examined the effects of prenatal drug exposure on adopted children's behavior, temperament, health, and school adjustment by comparing the experiences of 3 cohorts of children: (1) 320 drug-exposed children; (2) 456 children who were not drug exposed; and (3) 620 children whose drug exposure was unknown. Two years after placement no significant…

Examined links between early risk and problematic developmental outcomes in adopted children during middle childhood. Found no direct relation between prenatal, perinatal, or preplacement risk factors and problematic socioemotional adjustment. With 12 high-risk children, proactive cooperation among the child's adoptive and birth family members on…

Studies by many scientists have shown that the fetal period is the most important one for the development of a baby. It has been shown that this is the time when the basis for many diseases of the adult is formed. Among risk factors, the work environment is of considerable importance, as its influence on the woman's organism stands at 25 to 40…