This paper highlights one of the most critical aspects of facilitating vocabulary learning among children with autism. Several pertinent issues serve as the focus of the paper; vocabulary course design for high functioning children with autism and the relevant considerations required when teaching them using technology. To explore these issues, a qualitative design using content analysis through extensive literature review was conducted. The content analysis included a critical examination of the features of children with autism and their learning and the theories of vocabulary course design and its principles. The analysis brought to light relevant considerations following the five factors as identified from the critical examination of the literature. Hence, this paper proposes course design for high functioning children with autism considerations. Curriculum designers, syllabus writers and instructors for children with autism could expect to benefit from this paper. This paper also recommends quantitative research such as a survey with the relevant stakeholders to confirm or enrich the data from the present study.