The characteristics and major events of early American science are discussed in this paper. The philosophical influences and scientific practices of prominent scientists in early American time periods are examined and referenced in terms of their orientation to inquiry-oriented methods. Specific descriptions of the scientific accomplishments of Benjamin Silliman, Louis Agassiz, and Asa Gray are offered. The conditions and academic emphases found in higher education instructions and in secondary schools prior to and during the early 1900's are also highlighted. This historical review suggests that 19th century and early 20th century science was not conducive to planned inquiry, especially at higher levels of sophistication, and that in all probability lower levels of inquiry were accidental strategies in some 19th century American classrooms. Parallels are presented between the progression of science and the history of the teaching of science. (ML)