The COVID-19 pandemic is a public health emergency that has spread across Kentucky affecting all age groups. Scientific knowledge about this novel virus continues to evolve. The following guidelines are based upon what is known about mitigating risks of transmission across the Commonwealth to protect all populations. Protecting students and staff at educational facilities is necessary to reduce the spread in this environment and limit the community spread of COVID-19. These safety expectations were written with input from the Education Continuation Task Force as well as the Governor's Office, Department for Public Health, Kentucky Department of Education, the Cabinet of Education and Workforce Development and the Cabinet for Health and Family Services. Practices listed in this document are divided into safety expectations that must be implemented by schools as determined by the Kentucky Department for Public Health and the U.S. Centers for Disease Control and Prevention (CDC). Best practices are additional strategies that schools may choose to follow in order to optimize the safety of students and staff. The following safety expectations are fully explained in this guide: (1) social distancing; (2) cloth face coverings, school health policies, and personal protective equipment; (3) screening and school exclusion; (4) sanitation and environmental factors; and (5) contact tracing. Each of these sections include a detailed list of safety expectations and best practices followed by an at-a-glance overview for younger users. [This report was co-produced by Kentucky Public Health and the Kentucky Education & Workforce Development Cabinet. For a companion report, see ED611964.]