The National Institute of Justice (NIJ) developed the Comprehensive School Safety Initiative in consultation with federal partners and Congress. It is a research-focused initiative designed to increase the safety of schools nationwide through the development of knowledge regarding the most effective and sustainable school safety interventions and programs. Ultimately, the Initiative's goal is to develop improved strategies and models for comprehensive school safety. The Comprehensive School Safety Initiative program plan consists of three major parts presented in this report: (1) Understanding the history of school safety programs nationwide; (2) Conducting independent research and evaluation; and (3) Testing the effects of various school safety interventions via pilot projects. The following are appended: (1) Federal Databases Related to School Safety; (2) Technology Assessment Plan; (3) Investigator-Initiated Research: The Comprehensive School Safety Initiative Solicitation; (4) Dear Colleague Letter for Investigator Initiated Solicitation; (5) Developing Knowledge About What Works to Make Schools Safe Solicitation; and (6) Dear Colleague Letter Developing Knowledge Solicitation.