This document presents regulations regarding the implementation of certain sections of the Higher Education Act of 1965, as amended, and governs grants to local educational agencies to plan, establish, or operate teacher centers, and to institutions of higher education to operate teacher centers. The regulation also governs compensation to state educational agencies for services under the program. The document presents the purpose of teacher centers as understood by the legislation, an overview of the program and regulation, a summary of major issues, citations of legal authority, and the actual amendments to Title 45 of the Code of Federal Regulations regarding grants to the teacher centers program authorized by the Higher Education Act of 1965, as amended. (MJB)