Intended for teachers of severely handicapped students, the volume provides suggestions on systematic instruction based on individual assessment and curriculum development with sample detailed instructional sequences included. Explained in introductory chapters are the need for systematic instruction of the severely handicapped, major components of the individualization of instruction, and informal methods of assessment. The development of instructional materials and the instructional sequence format are considered in the section on curriculum development. The major portion of the document presents over 50 field tested instructional sequences ordered according to task and material. A chart is provided to help the reader locate specific sequences, with tasks such as matching, sorting, and recognizing; paired with materials such as objects, colors, and numbers. Each sequence is accompanied by a cover sheet listing the instructional objective, statement of need/relation to long range goal, prerequisite skills, materials required, means of initial assessment, reward/reward schedule, sequence and phase criteria, and maintenance activities. Some sample sequences are: motor imitation, simple picture match, color match, puzzle assembly, number recognition, object identification, and tactile discrimination of objects. Appended are a list of specific teacher competencies, guidelines for using the Area Learning Resource Centers network, and a list of component alternatives. (IM)