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Peer reviewedHalkides, Christopher J. – Journal of Chemical Education, 2004
Classical phenylketonuria (PKU) is caused by a lack activity in the enzyme phenylalanine hydroxylase, leading to elevated concentrations of phenylalanine in the blood. A simple demonstration and three advanced demonstrations of a spot test for phenylpyruvic acid and its relationship to phenylketonuria are given.
Descriptors: Demonstrations (Educational), Science Activities, Science Instruction, Chemistry
