This curriculum resource guide on alcohol and drug prevention provides suggested activities for teachers of grades 10 through 12. Three integrated learning activities for United States history and healthful living are presented. The history goals are understanding that the years since 1945 have been years of great changes, and learning to organize information and draw conclusions. Healthful living goals include understanding personal values, analyzing drug and alcohol use in terms of need fulfillment and personal goals, and demonstrating constructive problem solving. Each of these activities lists goals, content summary, resources, activity, and assessment. A curriculum integration activities feedback form and blank suggested activity forms are included. Information on relevant federal and state statutes and court cases is included. A summary of North Carolina laws and punishments on driving while intoxicated or under the influence of drugs is included. An article on search and seizure in public schools is reprinted. Information bulletins on these topics are provided: (1) the shared responsibility of drug and alcohol education; (2) alcohol; (3) amphetamines; (4) cocaine; (5) confidentiality requirements for school personnel; (6) depressants; (7) drugs and you; (8) fetal alcohol syndrome; (9) hallucinogens; (10) inhalants; (11) legal information for school personnel regarding student alcohol or drug use; (12) Lysergic Acid Diethylamide; (13) marijuana; (14) nicotine/cigarettes; and (15) steroids. (ABL)