The difficulties, mutual interests, and development of successful collaboration between high schools and colleges in achieving better access to and preparedness for higher education of the nation's high school graduates are addressed. It is noted that an increasing awareness of the changing student population, democratization of higher education admissions policies, the general lack of college-level academic skills, and a need for new models of inservice staff development for high school teachers, all point to an increasing interest in more intensive and successful secondary and postsecondary school partnerships. Factors such as the historical separation between secondary and postsecondary schools have created roadblocks to successful partnerships; it is noted that these inhibitors can be overcome. Examined are examples of high school-college partnerships, such as concurrent-enrollment models; enrichment, compensatory, and motivational designs; Academic Alliances and other teacher-to-teacher approaches; preservice teacher education; mentoring/tutoring models; and school improvement and restructuring efforts. Five key recommendations for developing any high school-college partnership are discussed: (1) identify the student population and program goals: (2) contact local high schools and school districts; (3) determine costs; (4) develop community support; and (5) evaluate the program improvement. Contains 112 references and an index. (GLR)