This project involved interfacing of microcomputers with three chemical instruments--Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), and the spectrophotometer. A Pascal program called "Spectrum" allows data from the NMR to be read and graphed, a specific area of the graph zoomed, ratios of specified areas of the graph measured, the range between points in hertz determined, the averaging out of a line, comparing and crossing of different graphs, moving a graph, and saving and retrieval of graphs in three different methods. The sweep of the NMR is also controlled by the analog/digital converter and the program when receiving data from the instrument. Real-time plots by controlling the sweep from the keyboard are also possible. The Pascal program written for the IR allows data from the IR to be read and graphed, specific areas of the graph to be enlarged, absorbance to be plotted, up to three graphs to be viewed at the same time, and saving and retrieval of graphs using three different methods. Voice synthesis was implemented with the spectrophotometer to aid the blind in controlling this instrument. The Pascal program can read and plot the data while reading the mode, wavelength, and data out loud at each increment. It can also read constantly at timed intervals for a blind person to make adjustments. Appendices illustrate circuit diagrams and connections between the interfaced instruments. (KR)