The first 5 years of life are a critical foundation for children's early learning and lifelong development. This eBulletin highlights school readiness, how early experiences matter, the role of preschool in supporting readiness, and state and local efforts to implement recommendations from the National Governors Association (NGA). The following Spotlights on SECC Work are included: (1) Alabama (Mary Lou Meadows); (2) Georgia (Glenda Copeland); (3) Louisiana (Robyn Madison-Harris); (4) Mississippi (Debra Meibaum); and (5) South Carolina (Beth Howard).