Traditionally, employment research related to people with disabilities has largely targeted the "supply-side"--employee-focused studies of personal and environmental factors that influence employment. These include age and gender, degree of impairment and work history, and access to housing, transportation, and health insurance. Although findings from such research are valuable, they provide an incomplete picture of problems and potential solutions and leave important questions unanswered. To provide a more complete picture of employment and balance the research agenda, it is crucial to recognize "demand-side" as an equally important part of the equation--employer-focused research on factors that affect employment practices. Among these are the size, culture, and goals of organizations that already employ or may hire people with disabilities. The Interagency Subcommittee on Employment (ISE) held the "Employer Perspectives on Workers with Disabilities: A National Summit to Develop a Research Agenda" to advance this research agenda. The Summit drew more than 70 researchers, business leaders, policy-makers, service providers, and advocates. Based on ISE preliminary plans submitted to the Steering Committee and the white papers, the committee narrowed the focus to six themes and recommended a framework for the Summit: (1) Changing the Employer/Worker Relationship--Methods Contributing to Industry Productivity and a Healthy Workforce; (2) Organizational Culture and Climate Regarding Disability Diversity in the Workforce; (3) Retention, Hiring, and Skills for the Future; (4) Business, Health, and Disability Management; (5) Demographics, Data, and Statistics for Employers; and (6) The Role and Effect of Government. This report provides a summary of: (1) keynote presentations; (2) panel-led discussion sessions across the six themes; (3) perspectives on the Summit; and (4) future directions. This Summit was the beginning of a dialogue among researchers, business leaders, policy-makers, and advocates on employer-side research. From the Summit's findings and from continuing dialogue, the ISE will create a national research agenda, supported across federal agencies, which will focus on the research needs of American industries and businesses. [This report was produced by MANILA Consulting Group, Inc. under U.S. Department of Labor, Office of Disability Employment Policy on behalf of the Interagency Committee on Disability Research (ICDR).]