This guide is a basic resource to help primary care providers offer quality care to lesbian, gay, and bisexual youth and their families. It is intended to be a minicourse, with three sections that combine background information, state-of-the-art research, practical guidelines, and reference information. After a foreword by Joan Holloway, part 1, "Overview: Lesbian and Gay Adolescents--Experiences and Needs," reviews lesbian and gay adolescents' needs and experiences, discussing identity development, health concerns, and confidentiality, and explaining how prejudice and fear of homosexuality are internalized and have social, behavioral, and health-related consequences. Part 2, "Primary Care and Prevention," discusses primary care and prevention needs, including guidance on health and mental health assessment and care for lesbian and gay youth. There is also information on transgendered youth, special populations, and family interventions. Part 3, "HIV/AIDS," reviews HIV infection in adolescents and discusses HIV counseling, testing, prevention, and clinical care. A series of appendixes offer information on (1) a 1994 conference created by a steering committee of experts on primary care for lesbian and gay youth; (2) resources on the primary care needs of lesbian and gay youth; (3) resources for parents and youth; (4) recommended reading for providers; (5) HIV counseling and testing protocol for adolescents (6) clinical care protocols; and (7) the American Academy of Pediatrics statements on homosexuality and adolescence. (SM)