"Middle College High Schools" are alternative high schools located on college campuses that aim to help at-risk students complete high school and encourage them to attend college. The four-year program offers a project-centered, interdisciplinary curriculum with an emphasis on team teaching, individualized attention, and the development of critical thinking skills. Students are also offered support services, including specialized counseling, peer support, and career experience opportunities. The What Works Clearing (WWC) reviewed 15 studies on "Middle College High School." One of these studies meets WWC evidence standards; the remaining 14 studies do not meet either WWC evidence standards or eligibility screens. Based on this one study, the WWC found the intervention to have no discernible effects on staying in school or completing school. The conclusions presented in this report may change as new research emerges. Six appendixes are included: (1) Study Characteristics; (2) Outcome Measures; (3) Summary of Study Findings; (4) Summary of Additional Findings; (5) Ratings; and (6) Extent of Evidence. (Contains 9 footnotes.)