In the recent years there has been a ten-fold increase in the incidence of autism in the USA. It is also estimated that approximately 67 million people are affected by autism worldwide. This worldwide epidemic has led to an increased interest in the identification and use of evidence-based interventions for individuals with autism. Interventions with children with autism can be broadly categorized into two primary types: (a) discrete trial training and (b) naturalistic interventions. This article provides an overview of the various components of evidence-based promising naturalistic interventions and their effectiveness with young children with autism. Naturalistic interventions that are reviewed in this article include pivotal response training, incidental teaching, and naturalistic language teaching paradigm. The evidence base for the interventions, limitations, and implications for practice are discussed. (Contains 2 tables.)