The year 2010 is historic because it marks the passage of a U.S. health-care reform bill as well as midterm elections that sent to Congress people looking to repeal it. Meanwhile, the public is waiting to see what it all means. It also saw the rise of personalized medicine, with genetics and electronic health records promising a more individualized approach to treatment, despite the fact many of the possible applications are still in the preliminary stages of research. Publishers responded to these developments with a fascinating selection of books--titles on the ethics of research and basic health guides for Latinas, seniors, and people with Down syndrome. In this article, the author presents a list of the best consumer health books of 2010.