HCI is a field which has an increasing popularity by virtue of the spread of the computers and internet and gradually contributes to the production of the user-friendlier software and hardware with the contribution of the scientists from different disciplines. Teacher candidates studying at the computer and instructional technologies department are individuals to take office in the field of instructional programs and software development. Acquaintance of teacher candidates studying at the computer and instructional technologies department with the HCI and its findings will enable such candidates to design usable websites and the achievement of message and interface design conforming to the rules. This research was conducted by using the phenomenological research method in order to determine the descriptions and perceptions of teacher candidates studying at the computer and instructional technologies department in respect of the human-computer interaction and respective basic concepts. Data gathered from the candidates by means of an open-ended question form were analyzed using descriptive analysis. According to the research results, it was seen that teacher candidates described the human-computer interaction and related basic concepts approximately close to the truth. (Contains 5 tables.)