Weight-based victimization (WBV) is a common and consequential experience for adolescents with overweight and obesity. The current study examined the relative contributions of different school-based sources of WBV (i.e., peers, friends, teachers, coaches) on academic grades, as well as the role of teachers in mitigating the academic consequences of WBV among a sample of 148 adolescents with high body weight (M[subscript age]= 15.97, SD[subscript age] = 1.25; 50% female). Regression analyses revealed that the link between school-based WBV and lower grades among adolescents was due primarily to mistreatment from peers. However, this association was weakened when students perceived their teachers to be more helpful in preventing future WBV, but not as a function of how frequently students reported incidents of WBV to their teachers. These findings underscore the importance of teacher intervention in supporting the academic success of adolescents experiencing WBV from their peers in the school setting.