This Research-to-Impact brief is the sixth in a series by Chapin Hall's Voices of Youth Count on understanding and addressing youth homelessness. This brief draws exclusively on the in-depth interview (IDI) component from Voices of Youth Count. The 215 young people that were interviewed across five diverse U.S. counties shared stories of instability--their pathways through homelessness--that highlighted missed opportunities for prevention and intervention. Insights point to critical areas for improvement: (1) the need for multilevel supports for individuals and families; (2) the importance of peers for building connections to trustworthy spaces and resources; and (3) the identification of specific changes that need to be made to service systems. This brief centers upon the insights and perspectives of young people whose contributions to society are profoundly inhibited. Their lives are needlessly constrained by the many opportunities we miss for protecting and fostering their healthy development and well-being. Findings support the unquestionable urgency of meeting the needs of young people for permanent housing and safety. These findings also emphasize that this period of time is developmentally significant and, therefore, developmental awareness must directly inform any strategy for addressing homelessness. These youths' stories highlight the consequences of chronic interpersonal trauma and loss, and the critical importance of safe emergency shelters and transitional housing. Their stories also show the urgent need to help youth and their families heal the adversity and trauma that preceded and persisted throughout their unaccompanied homelessness. The brief elevates the voices of youth as a call to adults to rethink and redouble their efforts in ending youth homelessness. Several key findings include: (1) Young people link the beginning of their homelessness to earlier disruptions of family and home, including family homelessness and entrance into foster care; (2) Young people name multilevel factors--critical conditions--that shaped how pathways through homelessness unfolded; and (3) Youth pathways through homelessness are also characterized by significant personal losses; 35% of youth experienced the death of at least one parent or primary caregiver. In addition to outlining the findings, this brief then connects those findings to recommended revisions to the federal Runaway and Homeless Youth Act, which authorizes community-based temporary shelter and care, and specifically targets services for minors. Revising the Act is likely to offer the most direct means to impact the programs and services that are intended to support young people like those who were interviewed. Beyond the recommendations, additional opportunities for change will likely expand outward to include other statutes and multiple federal agencies and program areas.