The objective of this research review is to synthesize research published between 2000 and 2015 regarding child sexual abuse, preschool and preschool teachers. The review identifies themes relevant for the preschool teacher profession: child sexual abuse at preschools, suspicions and consequences for the preschool sector, preventing techniques and the preschool teacher as a safeguarder. Furthermore, important types of tensions in efforts to safeguard against child sexual abuse are identified: the importance of listening to children and avoiding false allegations, the preschool teacher as a safeguarder and a potential abuser, and the importance of preventing child sexual abuse and providing qualitative care of children. Implications for the profession, the education of preschool teachers and the need for more research are addressed.