Wide entrepreneurship education (EE), based on constructivist pedagogies and effectual logic, emphasizes the inclusion of entrepreneurial attitudes and personal development as central EE components. Hence, the main aim of this study is examining how entrepreneurial attitudes and subjective well-being (SWB) are related with two additional personal resources necessary to thrive in an unpredictable and demanding labour market. Following constructivist educational recommendations, a full structural equation model was proposed and tested relating entrepreneurial attitudes, psychological capital, and self-care with SWB in a sample of 324 undergraduates. The findings revealed that self-care is a significant mediator, explaining 75.3% of SWB, and fully mediates the impact of psychological capital on SWB. However, self-care did not mediate the relationship between entrepreneurial attitudes and SWB. Intriguingly, a negative effect of entrepreneurial attitudes on SWB was observed. The study suggests mitigating this adverse impact by encouraging activities that foster self-care and psychological capital in university students.