There is currently no evidence of the relationship between cyber dating abuse (CDA) and health-related quality of life (HRQoL), especially from a longitudinal perspective. The objectives were: (a) to analyze the point and period prevalence, incidence, and score changes over time of victimization by CDA; (b) to compare HRQoL in the different categories of victims of CDA (nonvictims, new, ceased, intermittent, and stable victims). A three-wave longitudinal study was carried out over 13 months. The final sample was composed of adolescents who had a partner in the 6 months before the measurements: 341(W1), 357(W2), and 416(W3). The prevalence of CDA was 31.1% (W1), 32.8% (W2), and 18.1% (W3). The girls had higher prevalence in victimization by control than the boys in all waves. The period prevalence was 23% (20% for control, 15% for direct aggression) and the cumulative incidence was 15%. Stable victims had the lowest HRQoL scores.