Introduction: The work environment of professionals who work directly with people with intellectual disabilities plays a key role in people's lives, since they are directly or indirectly responsible for improving the living conditions of those who receive these services. Specifically, these workers' risk of suffering burnout has an important impact on the quality of the services provided by the organizations. This study analyzes the relationship between emotional intelligence and life satisfaction in professional burnout processes. Method: The sample is composed of 144 subjects (n=144), with an average age of 39.35 years (±9.06), belonging to the Andalusian Association of Organizations for Persons with Intellectual Disabilities (Full Inclusion). The following instruments are used: Satisfaction with Life Scale (SWLS), Maslach Burnout Inventory (MBI) and Emotional Quotient inventory (EQi-C). The Omega coefficient is used as it is a measure of reliability if the principle of equivalence is not met. Results: The results show the positive relationship between some of the dimensions of burnout, emotional intelligence, and life satisfaction (p<0.05). The regression analyses showed the positive association between emotional intelligence (adaptability and intrapersonal) and burnout (emotional fatigue) and life satisfaction. Discussion and conclusions: Practical consequences of this study suggest the implementation of Emotional Intelligence programs to acquire emotional competencies, as prevention measure of burnout among professionals who work directly with people with Intellectual Disability within organizations.