Considering the potential and popularity of social media it is important to inquire into its use in learning. In this study the implementation of the activity carried out in Twitter with higher education students was analysed. The research was conducted following a mixed methodology, based on virtual ethnography complemented by quantitative analysis of the tweets produced. A sample of 3,026 tweets was taken for such purpose. By way of conclusion, it is worth noting that student participation in the education process via Twitter progressively increases as their technical knowledge of this tool improves and they feel more motivated. Interaction and learning within a community is underpinned by gratifying experiences. Thus, the use of Twitter in the learning process of university students is feasible and perceived as a motivating experience by them. However, teachers play an essential role as dynamisers in the formal incorporation of Twitter in the teaching process, as well as in enhancing interaction between the participants.