In this study, the influence of socio-cultural factors on attitudes toward artificial intelligence (AI) was investigated. In total, 1,677 Korean middle school students were selected to participate, and a test tool was used to measure the attitude toward AI. As a result, according to socio-cultural factors, middle school students' attitudes toward AI were affected differently by gender- or AI-related experiences. In particular, students experiencing difficulties because of socio-cultural factors showed a more positive attitude toward AI if they had an AI education. On the other hand, interest toward AI and programming experience had a significant effect on attitudes toward AI and was not affected by socio-cultural factors. In particular, students with high interest toward AI or experience with block- and text-based programming languages showed significantly positive attitudes toward AI. Hence, the disparity in middle school students' attitude toward AI according to socio-cultural factors was found.