This study is an effort to understand the impact of occupational stress which is classified into four constructs i.e. pressure at work, support at work, job satisfaction, and nature of job, on the personality of employees working in public as well as private sector universities. To conduct the study, a survey questionnaire was floated to six universities: two public sector and four private sector. These universities were selected on convenience bases and respondents from these universities were selected based on purposive sampling technique. The data was found reliable through cronbach alpha. In order to analyse data, correlation followed by multiple regression were applied as statistical tools. Analysis showed that all variables of occupational stress have significant impact over employees' personality and overall model is significant at 99.9% confidence interval.