This 2016 Enrollment Report was prepared for the State Board of Higher Education by the North Dakota University System (NDUS). Enrollment trends highlighted herein include a one-year comparison for two-year institutions, four-year institutions, and system wide. Trends over the last five years and the last ten years are also described. For example, over the last five years, headcount in the NDUS has remained steady, decreasing overall by less than one percent or by a total of 370 students. Over this time period, the largest shift has been a decrease of students attending regional universities (-9.83% or -738 students), with the largest decrease occurring at DSU [Dakota State University] (-713 students) which experienced a -35.51% change in headcount. The ten-year NDUS headcount has increased 13.33% from 39,629 to 44,910. The system has currently 370 students less than the highest observed student headcount in Spring 2012 (n = 45,280), and 5,281 students more than the lowest observed student headcount in Spring 2007 (n = 39,629). Over the same ten-year time period, FTEs has increased by 2,495 or 7.61%. [For the 2016 Fall Enrollment Report, see ED572887.]