This study examined internal school quality assurance practices and undergraduate students' attitude towards academic activities in public universities in Cross River State, Nigeria. The study was guided by three null hypotheses and the design adopted was ex-post facto research design. The population of the study was made up of all the regular undergraduate students in their third year of study in the two public universities (University of Calabar and Cross River University of Technology) in Cross River State, Nigeria. The researchers used convenience sampling technique in selecting a sample of 2,500 students from the population which cut across the two public universities in the study area. Internal Quality Assurance Practices and Undergraduate Students' Attitude Towards Academic Activities Questionnaire (IQAPUSATAAQ) with Cronbach reliability reliabilities of 0.81, 0.86, 0.83, and 0.80 was the instrument used for data collection. Pearson Product Moment Correlation was the statistical tool used in testing the hypotheses at .05 level of significant. The results of the study revealed significant relationship between school quality assurance approaches (maintenance of facilities, curriculum implementation, examinations administration) and students' attitude towards academic activities. It was recommended among others that available teaching and learning facilities at the disposal of the management of universities should be maintained and made functional for the benefit of the students.