Work-life is believed to have either positive or negative effect on employees' job productivity especially among single-parent workers. The study investigated the relationship between single parent-teachers and their level of job productivity in public senior secondary schools in Edo State. To achieve this objective, four research questions were raised while three hypotheses were formulated therefrom. Two hundred and twenty-five single-parent teachers were purposively selected across the State-owned secondary schools in Edo State, Nigeria. Data were obtained through a structured questionnaire which was validated and tested for reliability level. The data collected were analyzed with the aid of descriptive and inferential statistics. Results obtained in the research indicated that single-parent teachers have low level of job productivity while their work-life balance was relatively less stressful. It was however found that there was no significant relationship between work-life balance and job productivity of single parent-teachers. Consequent upon this, it was recommended amongst others that school leadership should show more consideration to the personal and family needs of single-parent teachers especially; they should be innovative by using modern pedagogical tools for teaching and learning. Principals should step up their instructional supervisory roles, also, they should improve on their commitment to the welfare and working conditions of their staff members, especially the single parent teachers for improved job productivity.