Nigeria is a signatory to the Millennium Development Goals (MDGs) declaration but till now she has not made any significant milestones in actualizing these human development goals. In spite of the coordinated efforts towards mobilizing those in the formal education system to partially address its implementation challenges, serious gaps still exit in the implementation drive through the non-formal education. Most adults whose position and daily activities are critical to the successful actualization of the MDGs are excluded from the implementation programmes. Against this backdrop, this paper explores the relevance of non-formal education curriculum to the actualization of the Millennium Development Goals in Nigeria within the 2015 time frame.