Based on the past sixteen years of experience with an online collaborative endeavor offered across differing university types, as well as modes of instruction, the best practice found that by fostering student peer exchanges on a collaborative web site students reached a high level of achievement in these courses. Findings indicate that despite differences in institutions or modes of instruction, students were academically reflective in their peer discussions on the site across geographic boundaries. This best practice concludes that a collaboration with a peer interactive design has an important place in any discipline's goals. It provides the development, implementation, and evaluation of a collaborative interactive online teaching process for incorporation across any disciple, which is an ongoing concern for educators, program designers, university administrators, technical and administrative staff, institutional decision makers, training managers, and publishers on the development and delivery of pedagogical content.