From 2005 to 2011, the Gateway Institute for Pre-College Education partnered with three public entities in New York City--the Department of Education, the City University of New York and the Health and Hospitals Corporation--to introduce, educate, and prepare urban high school students for careers in the health professions. Gateway was launched in New York City in 1986 to prepare low-income and minority high school students for college and health and science-related careers. In interviews and reports to the Robert Wood Johnson Foundation (RWJF), project staff cited these results from the Gateway Health Careers project: (1) Gateway staff and its partners created a replicable model for introducing high school students to a broad array of health careers, which included health electives, hospital experiences and exposure to college programs; and (2) Eighty-five students at A. Philip Randolph Campus High School completed the program, which begins in the ninth grade and lasts until graduation, and 85 percent of those indicated they were interested in health careers. Most planned to attended a senior college to accomplish their health career goals (72% of the 2010 class and 59% of the 2011 class). Additional funders are appended. (Contains 2 footnotes.) [Additional funding for this paper was provided by Harlem Hospital Center, New York State STEP program, Sophie Davis School of Biomedical Education, and Hunter College School of Nursing.]