Interest in scaling promising innovations to effect systemic change in education around the world has grown over the last decade. The work of scaling education innovations (up, out, down, and into deep and lasting impact) has always required nimble attention to the unpredictability of implementation. Much has been written about the need for adaptive mindsets, planning for scale at the beginning, enlisting allies and champions, and embedding continuous improvement loops into the whole process (Al-Ubaydli, List, & Suskind, 2019; Gargani & McLean, 2019; Perlman Robinson, Curtiss, & Hannahan, 2020). As challenging as scaling is under ordinary 21st-century circumstances, it has become downright arduous over the last two years due to the global COVID-19 pandemic. This first annual brief reflects on scaling insights from different scaling teams across many low- and middle-income countries to jointly learn and share best practices related to scaling in education. Effective scaling is not just about designing and delivering promising innovations for use but also embedding them in thoughtful, mutifaceted ways to ensure that they grow, deepen, and have lasting impact. This brief discusses how several teams went about this work during the difficult last year. [This project is supported by the Global Partnership for Education Knowledge and Innovation Exchange (KIX), a joint partnership between the Global Partnership for Education (GPE) and the International Development Research Centre (IDRC).]