This guide replaces the 1975 publication "A Guide for Developing a Comprehensive K-12 School Health Instruction Program." It is designed to provide a framework for local curriculum development by identifying knowledge and skills students should master at each of four levels--grades K-3, 4-6, 7-9, and 10-12. At each level, the competencies and skills are organized into nine specific areas: (1) disease prevention and control; (2) family life and sex education; (3) mental health; (4) substance abuse; (5) nutrition; (6) personal health; (7) safety and first aid; (8) community health; and (9) consumer health. (JD)