While various innovative pedagogical methods have been proven effective in facilitating the development of students' English language skills in different contexts, this study explores the implementation of several innovative methods in one EMI course, which includes collaborative online international learning (COIL), content language integrated learning (CLIL), problem-posing education (PPE), and project-based learning (PBL). Deliberate considerations were made in choosing the methods: COIL to stimulate motivation; CLIL and PPE to promote content learning (input); and PBL to facilitate content-integrated learning outcomes (output). The course outcome was assessed with pre- and postcourse questionnaires on the use of English for communicative purposes. The findings suggest that the course was highly effective in promoting the development of participants' confidence, knowledge, and skills, with large effect sizes. Both participants' expectations for the course and the course objectives were met. The use of innovative methods strongly contributed to the positive outcomes of the course in this case.