This research aimed to study the influence of Leadership, Organizational Culture, Emotional Quotation, and Job Satisfaction to Teacher Performance of Senior High School at Palopo Municipality South Sulawesi. There were 78 teachers participated in this research. The results were: (1) Leadership directly affects teacher performance; (2) Emotional quotation directly influences teacher performance; (3) Job Satisfaction directly effects teacher performance; (4) Leadership directly effects job satisfaction; (5) Organizational Culture directly effects job satisfaction; (6) Emotional Quotation directly effects job satisfaction. Based on this research, the factors of Leadership, Organizational Culture, Emotional Quotation, and Job Satisfaction to Teacher Performance should be developed by Central and Local Government either Palopo or South Sulawesi, Indonesia.