The purpose of the study reported here was to investigate the impact of depository documents in CD-ROM format on academic federal depository libraries in Indiana. In the fall of 1992, a questionnaire was sent to all the federal academic depository libraries in Indiana. Topics covered in the questionnaire were the number of depository CD-ROMs received, their availability to the public, training of the staff, and levels of instruction given to the public in the use of these CD-ROMs. Based on the responses to the questionnaire, a dozen depository libraries in Indiana were selected to be visited. A more detailed list of questions was prepared including limits of use, location of CD-ROMs, and responses to new developments concerning CD-ROM technology. Analyses of the data indicated that: (1) most libraries dealt effectively with the CD-ROM format; (2) the number of depository CD-ROM titles received varied from three to all available; (3) over half of the libraries had not prepared their own user aids; and (4) instruction was given to patrons, but the quality of this instruction depended on the question, the patron, the knowledge of the staff, and how busy the staff were. Copies of the survey questionnaire and on-site questions are appended. (Contains 3 references.) (JLB)