This article examines the independent and interaction influence of organizational climate and the type of autonomous colleges on the academic performance of students. Organizational climate encompasses various elements such as leadership styles, communication patterns, and staff morale, collectively shaping the institutional environment. Autonomous colleges, with their capacity for innovation in curriculum design, pedagogical methods, and assessment practices, provide a unique context for this analysis. To explore the effect, researchers employed a quantitative approach, surveying 480 students across 12 colleges (both government and non-government) in Odisha, India. Questionnaires assessed student perceptions of organizational climate and academic achievement. Additionally, researchers collected student result sheets and surveyed college staff to gain a well-rounded perspective on the college climate. Data analysis using ANOVA and Scheffe tests identified significant effects. Major Findings of the study confirm that a positive organizational climate, regardless of college type, is associated with higher student academic achievement. Interestingly, students in government autonomous colleges achieved higher scores than those in non-government ones. The most significant finding, however, is the interaction effect. Students in government autonomous colleges with a strong learning environment achieved the highest scores, while those in non-government autonomous colleges with a weak environment achieved the lowest.