This paper illustrates the cloud-based telemonitoring framework that implements healthcare automation system for myocardial infarction (MI) disease classification. For this purpose, the pathological feature of ECG signal such as elevated ST segment, inverted T wave, and pathological Q wave are extracted, and MI disease is detected by the rule-based rough set classifier. The information system involves pathological feature as an attribute and decision class. The degree of attributes dependency finds a smaller set of attributes and predicted the comprehensive decision rules. For MI decision, the ECG signal is shared with the respective cardiologist who analyses and prescribes the required medication to the first-aid professional through the cloud. The first-aid professional is notified accordingly to attend the patient immediately. To avoid the identity crisis, ECG signal is being watermarked and uploaded to the cloud in a compressed form. The proposed system reduces both data storage space and transmission bandwidth which facilitates accessibility to quality care in much reduced cost.