This study examined how parents' perception of neighborhood conditions are associated with school absenteeism and participation in afterschool activities, and how social support networks moderate those linkages among two-parent and single-parent families. Data from the second and third Waves of the "Making Connections" Survey were analyzed. A subsample of 1,053 Latina/o parents with 10-17-year-old children was examined. Longitudinal path analyses suggest an indirect positive association between neighborhood control and participation in organized afterschool activities via instrumental social support, but only among two-parent families. Neighborhood cohesion was associated with school days missed and participation in organized afterschool activities among single-parent families. Implications for practice and policy are discussed.