This study reports the results of a single-arm, noncontrolled, Type 3 hybrid effectiveness-implementation trial evaluating virtual reality job interview training (VR-JIT) delivered in five preemployment transition programs comprising 15 schools, 10 administrators, 23 teachers, and 279 youth ages 16-21 years receiving special education preemployment transition services. Fidelity, expected implementation feasibility, and teacher and student acceptance of VR-JIT were high. Youth completed virtual interviews (M = 10.8, SD = 7.4) over 6-8 weeks. At the 6-month follow-up, teachers reported that youth using VR-JIT had employment rates higher than current national employment rates for youth with disabilities. A multinomial logistic regression revealed VR-JIT engagement was associated with greater employment rates by 6-month follow-up (odds ratio = 1.63, p = 05663.002). This study provides promising evidence that VR-JIT may be feasibly implemented with high fidelity in special education preemployment transition services and can potentially enhance employment outcomes among transition-age youth receiving special education services.