Adolescents from low-income families generally have limited resources, which may negatively impact their career development. This study reports findings from the Youth Work-Explorer (Y-WE) career development program for 519 high-school students from low-income families in Hong Kong. One hundred forty-six participants received a three-day career training workshop plus work-attachment Y-WE intervention (group A); 190 received only Y-WE intervention (group B); 183 students were recruited as the control group received no intervention during the study. All participants completed a questionnaire containing three scales measuring extroversion, career knowledge, and career decision self-efficacy (CDSE) twice before and after the intervention. Relative T-tests and repeated measures analysis of variance (ANOVA) were used to determine the intervention's effectiveness. Results indicated that compared with the control group, participants in group A significantly improved in extroversion and career knowledge, while participants in group B significantly increased their career knowledge and CDSE.