Gifted students have unique educational needs. Although gifted students are as varied as other students in terms of their learning styles and preferences, all gifted learners have exhibited unusual performance or potential and they have distinctive characteristics, shared by most of these students, which require effective responses from educators. Research indicates that gifted students typically feel responsible for their own learning and often learn best alone; they may not need the structure provided by external organization of content and activities. Gifted students also tend to prefer tactile and kinesthetic learning, and may not respond as well to auditory learning modes. These students understand complex ideas, enjoy theory, and often prefer abstract themes and concepts. Gifted students tend to be open and flexible in their learning and to value logic and objectivity (Thomson, 2010). The characteristics gifted and talented students share present a challenge to educators. They must find ways to help these students learn effectively. Information technology offers a means to meet the challenge by merging research-based best practices for these students with online learning. This paper provides best practices in virtual learning environments for gifted students. An annotated bibliography is included.