Scientists are often described as smart and logical thinkers but lacking in the so-called "soft skills." Well-known TV series such as "The Big Bang Theory" and "Breaking Bad" have also shaped these stereotypical ideas in society. In the present study, a total of 1013 students in grades 8 and 11 were asked about factors that influenced a chemistry-related career choice. Since interest is considered an important factor influencing the career choice, the focus of this study was placed on images and stereotypes compared with academic self-concepts. The models calculated by multiple linear regressions showed significant differences in relation to grades but insignificant in terms of school type. A chemistry-related career choice of 11th grade students was based on the image of chemistry lessons and the distance between self-description and the view of a stereotypical chemical prototype whereas in grade 8 factors such as their grade in chemistry or factors of the academic self-concept also influenced this decision. The results point out the need to promote vocational orientation in chemistry lessons. It is particularly important that students have the opportunity to form a realistic image of chemists.