With the continuous development of embodied cognition theory and virtual reality (VR) technology, its application in teaching has been paid more and more attention by researchers. However, there are still few practical studies on the combination of VR technology and embodied learning. Starting from literature research, the paper analyzes the factors that affect the embodied learning in the VR environment; then, put forward the design principles under the support of VR based on the previous studies; finally, constructs the embodied learning design framework, combined with the two parts of study. The research chooses a course (namely "Discrete Mathematics") as an example of embodied learning design case, which organizes the application facing college students in Computer Science and Technology major of Nanchang Institute of Technology. The study found that the body is indeed involved in the cognitive process, and the embodied learning based on VR can effectively improve the learning achievement and has a positive impact on learners' learning participation and interest in learning during the experiment.