Since 1840, Chinese political leaders have struggled to draw effectively from Western culture without abandoning the Chinese essence in their design of higher education. In this paper, we use cultural nationalism as the theoretical framework to examine how Chinese political leaders have responded to this challenge. Our analysis shows that cultural nationalism closely links to politics, and although the form taken by cultural nationalism has varied throughout Chinese history, it has significantly influenced Chinese higher education. In particular, we identify a strong cultural nationalism in today's China, which has already influenced teaching and research in Chinese higher education. Finally, we discuss the implications and limitations of this paper, and call for critical reflections of cultural nationalism and its impact on Chinese higher education.