This study examines the use of critical questions (CQs) as an 'explicit' pedagogical method in the nature of science to teach Chinese high school students topics of philosophy of science (POS). The study results, evaluated through deductive thematic and qualitative comparative analyses using Toulmin's argumentation patterns and a critical integrative argumentation model, revealed that students who participated in the POS course showed significant improvement in understanding and application of argumentation by asking CQs as suggested by instructors. This finding strongly supports the use of CQs for rebuttals in argumentation based on crisp qualitative comparative analysis. The study results have broad implications for how CQs can promote engagement in high school argumentation. The study conclusions highlight the limitations of oral questioning in classroom argumentation. Finally, the study discusses how POS can improve students' classroom argumentation.