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The Interacting Effect of the BDNF Val66Met Polymorphism and Stressful Life Events on Adolescent Depression Is Not an Artifact of Gene-Environment Correlation: Evidence from a Longitudinal Twin Study
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Chen, Jie; Li, Xinying; McGue, Matt – Journal of Child Psychology and Psychiatry, 2013
Background: Confounding introduced by gene-environment correlation (rGE) may prevent one from observing a true gene-environment interaction (G × E) effect on psychopathology. The present study investigated the interacting effect of the BDNF Val66Met polymorphism and stressful life events (SLEs) on adolescent depression while controlling for the…
Descriptors: Depression (Psychology), Symptoms (Individual Disorders), Foreign Countries, Adolescents