Existing literature on international health partnerships is largely normative, with an evaluative interest in their impacts in terms of learning and knowledge transfer. Rarely has research attended to how learning and knowledge transfer transpire in practice. This paper addresses this gap with a case study of a partnership between two hospitals in Canada and China. Conceptually, drawing on Actor Network Theory, it posits learning and knowledge transfer as a process of translation. Empirically, it traces the assembling of the programme, and identifies the pedagogical features at nodes of associations. It reveals that health professionals in both countries have expanded their clinical and medical knowledge and practices, and professional senses and sensitivities, which were subsequently amplified, deferred or diminished within their respective practices. It argues that the capacity of individuals to translate learning into practice is contingent on institutional and cultural differences that constitute the ecology of work for health professionals.